Drug interactions
Mycophenolate mofetil + Ticarcillin
Severity: Minor
Mycophenolate mofetil and Ticarcillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ticarcillin is a penicillin eliminated by renal tubular secretion and may compete with the mycophenolic acid glucuronide metabolite. The effect is theoretical and usually small, though antibiotics may also lower mycophenolic acid exposure through reduced enterohepatic recycling.
What this interaction means in plain words
Mycophenolate mofetil and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular secretion and antibiotic-related reduction in enterohepatic recycling.
What to do
No dose change is routinely required; monitor graft function and clinical response during prolonged antibiotic therapy, especially with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Frequently asked questions
Can I take Mycophenolate mofetil with Ticarcillin?
MediHelp rates the interaction as minor. Mycophenolate mofetil and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ticarcillin is a penicillin eliminated by renal tubular secretion and may compete with the mycophenolic acid glucuronide metabolite. The effect is theoretical and usually small, though antibiotics may also lower mycophenolic acid exposure through reduced enterohepatic recycling.
How serious is the interaction between Mycophenolate mofetil and Ticarcillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is routinely required; monitor graft function and clinical response during prolonged antibiotic therapy, especially with renal impairment.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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