Drug interactions
Mycophenolate mofetil + Tick-borne encephalitis vaccine
Severity: Moderate
Mycophenolate mofetil and Tick-borne encephalitis vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The tick-borne encephalitis vaccine is inactivated, so the issue is a possibly weaker antibody response in mycophenolate-treated patients. Protection may be incomplete in endemic areas.
What this interaction means in plain words
Mycophenolate mofetil and Tick-borne encephalitis vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Lymphocyte suppression via IMPDH inhibition blunts vaccine response.
What to do
Complete the series before exposure and consider checking antibody levels. Reinforce tick-bite avoidance measures.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Frequently asked questions
Can I take Mycophenolate mofetil with Tick-borne encephalitis vaccine?
MediHelp rates the interaction as moderate. Mycophenolate mofetil and Tick-borne encephalitis vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The tick-borne encephalitis vaccine is inactivated, so the issue is a possibly weaker antibody response in mycophenolate-treated patients. Protection may be incomplete in endemic areas.
How serious is the interaction between Mycophenolate mofetil and Tick-borne encephalitis vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the series before exposure and consider checking antibody levels. Reinforce tick-bite avoidance measures.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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