Drug interactions
Nabilone + Phenylephrine po
Severity: Minor
Nabilone and Phenylephrine po: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral phenylephrine is a decongestant with modest pressor activity, and nabilone may cause tachycardia and blood pressure changes. A mild additive cardiovascular effect is possible, but there is no reliable interaction on sedation.
What this interaction means in plain words
Nabilone and Phenylephrine po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive cardiovascular effects from alpha-adrenergic agonism and cannabinoid activity; not well established.
What to do
Monitor heart rate and blood pressure in patients with cardiovascular disease. No routine dose adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nabilone
Frequently asked questions
Can I take Nabilone with Phenylephrine po?
MediHelp rates the interaction as minor. Nabilone and Phenylephrine po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral phenylephrine is a decongestant with modest pressor activity, and nabilone may cause tachycardia and blood pressure changes. A mild additive cardiovascular effect is possible, but there is no reliable interaction on sedation.
How serious is the interaction between Nabilone and Phenylephrine po?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure in patients with cardiovascular disease. No routine dose adjustment is needed.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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