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Drug interactions

Nabilone + Scullcap

Severity: Moderate

Nabilone and Scullcap: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Skullcap is a herbal product traditionally used for its calming effects and may add to the drowsiness caused by nabilone. The evidence is theoretical.

What this interaction means in plain words

Nabilone and Scullcap can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Presumed additive CNS depression from herbal sedative activity; not well established.

What to do

Advise patients to avoid skullcap while taking nabilone, and monitor for excess drowsiness if used.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Nabilone with Scullcap?

MediHelp rates the interaction as moderate. Nabilone and Scullcap can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Skullcap is a herbal product traditionally used for its calming effects and may add to the drowsiness caused by nabilone. The evidence is theoretical.

How serious is the interaction between Nabilone and Scullcap?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid skullcap while taking nabilone, and monitor for excess drowsiness if used.

What other medicines interact with Nabilone?

MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.

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