Drug interactions
Nabilone + Triclofos
Severity: Moderate
Nabilone and Triclofos: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclofos is a sedative-hypnotic whose active metabolite is trichloroethanol, and it can add to the sedative effect of nabilone. The combination may cause excessive drowsiness, impaired alertness and reduced coordination.
What this interaction means in plain words
Nabilone and Triclofos can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression between a cannabinoid agonist and a chloral-derivative hypnotic.
What to do
Monitor for excessive sedation and reduce the dose of one or both agents if it develops. Advise patients not to drive or use alcohol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Frequently asked questions
Can I take Nabilone with Triclofos?
MediHelp rates the interaction as moderate. Nabilone and Triclofos can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclofos is a sedative-hypnotic whose active metabolite is trichloroethanol, and it can add to the sedative effect of nabilone. The combination may cause excessive drowsiness, impaired alertness and reduced coordination.
How serious is the interaction between Nabilone and Triclofos?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and reduce the dose of one or both agents if it develops. Advise patients not to drive or use alcohol.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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