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Drug interactions

Nadolol + Terazosin

Severity: Moderate

Nadolol and Terazosin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Concurrent use produces additive blood pressure reduction, with a risk of orthostatic hypotension and dizziness, especially when starting or increasing terazosin.

What this interaction means in plain words

Nadolol and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nadolol belongs to Cardiovascular; Terazosin belongs to Genitourinary.

Evidence level: Moderate

Why it happens

Additive pharmacodynamic hypotension from alpha-1 and nonselective beta-blockade.

What to do

Titrate terazosin slowly from a low starting dose and monitor orthostatic blood pressure.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Nadolol with Terazosin?

MediHelp rates the interaction as moderate. Nadolol and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Concurrent use produces additive blood pressure reduction, with a risk of orthostatic hypotension and dizziness, especially when starting or increasing terazosin.

How serious is the interaction between Nadolol and Terazosin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate terazosin slowly from a low starting dose and monitor orthostatic blood pressure.

What other medicines interact with Terazosin?

MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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