Drug interactions
Nadolol + Timolol
Severity: Moderate
Nadolol and Timolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Two beta-blockers taken together give duplicated beta-blockade. This raises the risk of symptomatic bradycardia, hypotension, AV conduction block and bronchospasm.
What this interaction means in plain words
Nadolol and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nadolol belongs to Cardiovascular; Timolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic beta-adrenergic receptor antagonism.
What to do
Avoid combining two beta-blockers; choose a single agent. If unavoidable, monitor heart rate and blood pressure and adjust doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Frequently asked questions
Can I take Nadolol with Timolol?
MediHelp rates the interaction as moderate. Nadolol and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Two beta-blockers taken together give duplicated beta-blockade. This raises the risk of symptomatic bradycardia, hypotension, AV conduction block and bronchospasm.
How serious is the interaction between Nadolol and Timolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining two beta-blockers; choose a single agent. If unavoidable, monitor heart rate and blood pressure and adjust doses.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
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