Drug interactions
Neomycin + Vitamin a
Severity: Minor
Neomycin and Vitamin a: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin can impair intestinal fat absorption and may reduce absorption of fat-soluble vitamins such as vitamin A. This is mainly relevant with prolonged oral neomycin use and could contribute to lower vitamin A status.
What this interaction means in plain words
Neomycin and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Neomycin belongs to Anti Bacterial; Vitamin a belongs to Gastrointestinal Tract.
Why it happens
Neomycin causes intestinal mucosal changes and bile acid precipitation, which impairs fat and fat-soluble vitamin absorption.
What to do
No routine action is needed for short courses; during prolonged oral neomycin therapy, monitor for signs of vitamin A deficiency and supplement if indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Neomycin
- Amikacin + Neomycin Major
- Amphotericin b deoxycholate + Neomycin Major
- Capreomycin + Neomycin Major
- Cidofovir + Neomycin Major
- Colistin + Neomycin Major
- Ethacrynic acid + Neomycin Major
Other interactions of Vitamin a
- Acitretin + Vitamin a Major
- Etretinate + Vitamin a Major
- Isotretinoin + Vitamin a Major
- Palovarotene + Vitamin a Major
- Bexarotene + Vitamin a Moderate
- Minocycline + Vitamin a Moderate
Frequently asked questions
Can I take Neomycin with Vitamin a?
MediHelp rates the interaction as minor. Neomycin and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin can impair intestinal fat absorption and may reduce absorption of fat-soluble vitamins such as vitamin A. This is mainly relevant with prolonged oral neomycin use and could contribute to lower vitamin A status.
How serious is the interaction between Neomycin and Vitamin a?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed for short courses; during prolonged oral neomycin therapy, monitor for signs of vitamin A deficiency and supplement if indicated.
What other medicines interact with Neomycin?
MediHelp also lists interactions of Neomycin with, for example, Amikacin, Amphotericin b deoxycholate, Capreomycin. The full list is on the Neomycin page.
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