Drug interactions
Nicardipine + Timolol
Severity: Minor
Nicardipine and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Timolol and nicardipine both lower blood pressure, so hypotension may be more pronounced when used together. Nicardipine has less effect on conduction than verapamil or diltiazem, but negative inotropy can matter in patients with poor ventricular function.
What this interaction means in plain words
Nicardipine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nicardipine belongs to Cardiovascular; Timolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic effects of beta-blockade and calcium channel blocker vasodilation.
What to do
Monitor blood pressure and heart rate when starting or adjusting doses. Take extra care in patients with heart failure or conduction disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Other interactions of Nicardipine
Frequently asked questions
Can I take Nicardipine with Timolol?
MediHelp rates the interaction as minor. Nicardipine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Timolol and nicardipine both lower blood pressure, so hypotension may be more pronounced when used together. Nicardipine has less effect on conduction than verapamil or diltiazem, but negative inotropy can matter in patients with poor ventricular function.
How serious is the interaction between Nicardipine and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting doses. Take extra care in patients with heart failure or conduction disease.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
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