Drug interactions
Nisoldipine + Rabeprazole
Severity: Minor
Nisoldipine and Rabeprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nisoldipine has a coat-core formulation, and changes in gastric pH have not been shown to produce a clinically important effect on its exposure. A meaningful interaction with rabeprazole is not established.
What this interaction means in plain words
Nisoldipine and Rabeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nisoldipine belongs to Cardiovascular; Rabeprazole belongs to Gastrointestinal Tract.
Why it happens
Altered gastric pH could theoretically change nisoldipine absorption, but no established mechanism exists.
What to do
No specific action is needed; monitor blood pressure as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rabeprazole
- Rabeprazole + Rilpivirine Contraindicated
- Acalabrutinib + Rabeprazole Major
- Atazanavir + Rabeprazole Major
- Dacomitinib + Rabeprazole Major
- Dasatinib + Rabeprazole Major
- Erlotinib + Rabeprazole Major
Other interactions of Nisoldipine
- Itraconazole + Nisoldipine Contraindicated
- Ketoconazole + Nisoldipine Contraindicated
- Apalutamide + Nisoldipine Major
- Carbamazepine + Nisoldipine Major
- Chloramphenicol + Nisoldipine Major
- Clarithromycin + Nisoldipine Major
Frequently asked questions
Can I take Nisoldipine with Rabeprazole?
MediHelp rates the interaction as minor. Nisoldipine and Rabeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nisoldipine has a coat-core formulation, and changes in gastric pH have not been shown to produce a clinically important effect on its exposure. A meaningful interaction with rabeprazole is not established.
How serious is the interaction between Nisoldipine and Rabeprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor blood pressure as usual.
What other medicines interact with Rabeprazole?
MediHelp also lists interactions of Rabeprazole with, for example, Rilpivirine, Acalabrutinib, Atazanavir. The full list is on the Rabeprazole page.
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