Drug interactions
Nitroglycerin rectal + Torsemide
Severity: Moderate
Nitroglycerin rectal and Torsemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nitroglycerin and torsemide both lower blood pressure, and combined use may cause additive hypotension. Volume depletion increases the risk of dizziness and syncope.
What this interaction means in plain words
Nitroglycerin rectal and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypotensive effects from venodilation and diuretic-induced volume reduction.
What to do
Monitor blood pressure and orthostatic symptoms and keep the patient well hydrated. Reduce the dose of either drug if hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Torsemide
Frequently asked questions
Can I take Nitroglycerin rectal with Torsemide?
MediHelp rates the interaction as moderate. Nitroglycerin rectal and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nitroglycerin and torsemide both lower blood pressure, and combined use may cause additive hypotension. Volume depletion increases the risk of dizziness and syncope.
How serious is the interaction between Nitroglycerin rectal and Torsemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms and keep the patient well hydrated. Reduce the dose of either drug if hypotension occurs.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
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