Drug interactions
Oliceridine + Triamterene
Severity: Minor
Oliceridine and Triamterene: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Opioids can cause antidiuretic hormone release and may blunt diuretic response. They can also cause hypotension, which may be additive with triamterene. The effect is usually modest and short-lived.
What this interaction means in plain words
Oliceridine and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oliceridine belongs to Musculoskeletal; Triamterene belongs to Cardiovascular.
Why it happens
Opioid-induced ADH release reducing diuresis, plus additive hypotensive effects.
What to do
Monitor urine output, volume status, and blood pressure, and adjust the diuretic dose if response is diminished.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Triamterene
- Amiloride + Triamterene Contraindicated
- Eplerenone + Triamterene Contraindicated
- Potassium citrate / citric acid + Triamterene Contraindicated
- Potassium citrate + Triamterene Contraindicated
- Spironolactone + Triamterene Contraindicated
- Aceclofenac + Triamterene Major
Other interactions of Oliceridine
- Isocarboxazid + Oliceridine Contraindicated
- Alprazolam + Oliceridine Major
- Amiodarone + Oliceridine Major
- Amisulpride + Oliceridine Major
- Amitriptyline + Oliceridine Major
- Amobarbital + Oliceridine Major
Frequently asked questions
Can I take Oliceridine with Triamterene?
MediHelp rates the interaction as minor. Oliceridine and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Opioids can cause antidiuretic hormone release and may blunt diuretic response. They can also cause hypotension, which may be additive with triamterene. The effect is usually modest and short-lived.
How serious is the interaction between Oliceridine and Triamterene?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor urine output, volume status, and blood pressure, and adjust the diuretic dose if response is diminished.
What other medicines interact with Triamterene?
MediHelp also lists interactions of Triamterene with, for example, Amiloride, Eplerenone, Potassium citrate / citric acid. The full list is on the Triamterene page.
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