Drug interactions
Olmesartan + Potassium iodide
Severity: Moderate
Olmesartan and Potassium iodide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide contains potassium, which can add to the hyperkalemic tendency of olmesartan. Risk is mainly relevant with prolonged or high-dose iodide use or reduced kidney function.
What this interaction means in plain words
Olmesartan and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Olmesartan belongs to Cardiovascular; Potassium iodide belongs to Endocrine.
Why it happens
Reduced aldosterone-dependent potassium excretion from angiotensin receptor blockade combined with additional potassium intake.
What to do
Monitor serum potassium if potassium iodide is used for more than a short course, especially in renal impairment. Reduce or stop the iodide if hyperkalemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Olmesartan
- Aliskiren + Olmesartan Contraindicated
- Olmesartan + Sparsentan Contraindicated
- Aldesleukin + Olmesartan Major
- Amifostine + Olmesartan Major
- Amiloride + Olmesartan Major
- Amlodipine-benazepril + Olmesartan Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Olmesartan with Potassium iodide?
MediHelp rates the interaction as moderate. Olmesartan and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Potassium iodide contains potassium, which can add to the hyperkalemic tendency of olmesartan. Risk is mainly relevant with prolonged or high-dose iodide use or reduced kidney function.
How serious is the interaction between Olmesartan and Potassium iodide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if potassium iodide is used for more than a short course, especially in renal impairment. Reduce or stop the iodide if hyperkalemia occurs.
What other medicines interact with Olmesartan?
MediHelp also lists interactions of Olmesartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Olmesartan page.
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