Drug interactions
Olodaterol inhaled + Voriconazole
Severity: Moderate
Olodaterol inhaled and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole prolongs the QT interval and olodaterol, a long-acting beta2 agonist, can have cardiovascular effects including QT changes and hypokalemia. Systemic exposure from inhalation is low, so the risk is mainly in patients with other arrhythmia risk factors.
What this interaction means in plain words
Olodaterol inhaled and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta2-agonist cardiovascular effects, with possible hypokalemia.
What to do
Monitor the ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Correct electrolyte disturbances.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Olodaterol inhaled with Voriconazole?
MediHelp rates the interaction as moderate. Olodaterol inhaled and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voriconazole prolongs the QT interval and olodaterol, a long-acting beta2 agonist, can have cardiovascular effects including QT changes and hypokalemia. Systemic exposure from inhalation is low, so the risk is mainly in patients with other arrhythmia risk factors.
How serious is the interaction between Olodaterol inhaled and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Correct electrolyte disturbances.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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