Drug interactions
Opuntia ficus indica + Rosiglitazone
Severity: Minor
Opuntia ficus indica and Rosiglitazone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prickly pear cactus has reported glucose-lowering activity and may add to the effect of rosiglitazone. Hypoglycemia is possible but unlikely to be severe.
What this interaction means in plain words
Opuntia ficus indica and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive pharmacodynamic glucose-lowering effect.
What to do
Monitor blood glucose when the supplement is started or stopped. Adjust rosiglitazone only if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Insulin aspart + Rosiglitazone Major
- Insulin degludec / insulin aspart + Rosiglitazone Major
- Insulin degludec-insulin aspart + Rosiglitazone Major
- Insulin degludec-liraglutide + Rosiglitazone Major
Frequently asked questions
Can I take Opuntia ficus indica with Rosiglitazone?
MediHelp rates the interaction as minor. Opuntia ficus indica and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Prickly pear cactus has reported glucose-lowering activity and may add to the effect of rosiglitazone. Hypoglycemia is possible but unlikely to be severe.
How serious is the interaction between Opuntia ficus indica and Rosiglitazone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when the supplement is started or stopped. Adjust rosiglitazone only if hypoglycemia occurs.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
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