Drug interactions
Oxaliplatin + Rabies vaccine chick embryo cell derived
Severity: Moderate
Oxaliplatin and Rabies vaccine chick embryo cell derived: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxaliplatin may reduce the immune response to chick embryo cell rabies vaccine. A poor response is important because rabies is almost always fatal once symptoms develop.
What this interaction means in plain words
Oxaliplatin and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Cytotoxic myelosuppression and lymphopenia blunt the immune response to vaccine antigens.
What to do
Do not delay post-exposure prophylaxis, and measure neutralizing antibody titers after the series in patients on chemotherapy; complete pre-exposure vaccination before treatment if possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Frequently asked questions
Can I take Oxaliplatin with Rabies vaccine chick embryo cell derived?
MediHelp rates the interaction as moderate. Oxaliplatin and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxaliplatin may reduce the immune response to chick embryo cell rabies vaccine. A poor response is important because rabies is almost always fatal once symptoms develop.
How serious is the interaction between Oxaliplatin and Rabies vaccine chick embryo cell derived?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not delay post-exposure prophylaxis, and measure neutralizing antibody titers after the series in patients on chemotherapy; complete pre-exposure vaccination before treatment if possible.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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