Drug interactions
Oxaprozin + Valganciclovir
Severity: Minor
Oxaprozin and Valganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxaprozin may compete with ganciclovir, the active form of valganciclovir, for renal tubular secretion. This could modestly raise ganciclovir exposure and increase hematologic or other dose-related toxicity, particularly in patients with reduced kidney function. Clinical significance is uncertain.
What this interaction means in plain words
Oxaprozin and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oxaprozin belongs to Musculoskeletal; Valganciclovir belongs to Anti Virals.
Why it happens
Competition for renal tubular secretion via organic anion transporters may reduce ganciclovir clearance.
What to do
Monitor complete blood counts and renal function if used together, and adjust valganciclovir dose to creatinine clearance as per labeling.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxaprozin
- Ketorolac intranasal + Oxaprozin Contraindicated
- Ketorolac + Oxaprozin Contraindicated
- Aceclofenac + Oxaprozin Major
- Acemetacin + Oxaprozin Major
- Acetylsalicylic acid + Oxaprozin Major
- Alteplase + Oxaprozin Major
Other interactions of Valganciclovir
Frequently asked questions
Can I take Oxaprozin with Valganciclovir?
MediHelp rates the interaction as minor. Oxaprozin and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxaprozin may compete with ganciclovir, the active form of valganciclovir, for renal tubular secretion. This could modestly raise ganciclovir exposure and increase hematologic or other dose-related toxicity, particularly in patients with reduced kidney function. Clinical significance is uncertain.
How serious is the interaction between Oxaprozin and Valganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts and renal function if used together, and adjust valganciclovir dose to creatinine clearance as per labeling.
What other medicines interact with Oxaprozin?
MediHelp also lists interactions of Oxaprozin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Oxaprozin page.
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