Drug interactions
Oxymetholone + Rosiglitazone
Severity: Minor
Oxymetholone and Rosiglitazone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxymetholone, an anabolic steroid, can reduce blood glucose and enhance sensitivity to antidiabetic drugs. Combined with rosiglitazone, glucose may fall further and hypoglycemia may occur.
What this interaction means in plain words
Oxymetholone and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive pharmacodynamic effect on glucose metabolism through improved insulin sensitivity.
What to do
Monitor blood glucose when oxymetholone is started or stopped. Lower the antidiabetic dose if hypoglycemia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Insulin aspart + Rosiglitazone Major
- Insulin degludec / insulin aspart + Rosiglitazone Major
- Insulin degludec-insulin aspart + Rosiglitazone Major
- Insulin degludec-liraglutide + Rosiglitazone Major
Frequently asked questions
Can I take Oxymetholone with Rosiglitazone?
MediHelp rates the interaction as minor. Oxymetholone and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxymetholone, an anabolic steroid, can reduce blood glucose and enhance sensitivity to antidiabetic drugs. Combined with rosiglitazone, glucose may fall further and hypoglycemia may occur.
How serious is the interaction between Oxymetholone and Rosiglitazone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when oxymetholone is started or stopped. Lower the antidiabetic dose if hypoglycemia develops.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
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