Drug interactions
Pentazocine + Sage
Severity: Minor
Pentazocine and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage is a herbal product with some reported sedative properties, and pentazocine causes sedation. The additive effect on drowsiness is theoretical and the clinical significance is uncertain.
What this interaction means in plain words
Pentazocine and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depressant effects; the mechanism for sage is not well established.
What to do
No routine change is needed; advise patients to watch for excess drowsiness and avoid driving if affected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pentazocine
- Calcium / magnesium / potassium / sodium oxybates + Pentazocine Contraindicated
- Olanzapine / samidorphan + Pentazocine Contraindicated
- Pentazocine + Phenelzine Contraindicated
- Pentazocine + Tranylcypromine Contraindicated
- Alfentanil + Pentazocine Major
- Alprazolam + Pentazocine Major
Frequently asked questions
Can I take Pentazocine with Sage?
MediHelp rates the interaction as minor. Pentazocine and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage is a herbal product with some reported sedative properties, and pentazocine causes sedation. The additive effect on drowsiness is theoretical and the clinical significance is uncertain.
How serious is the interaction between Pentazocine and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; advise patients to watch for excess drowsiness and avoid driving if affected.
What other medicines interact with Pentazocine?
MediHelp also lists interactions of Pentazocine with, for example, Calcium / magnesium / potassium / sodium oxybates, Olanzapine / samidorphan, Phenelzine. The full list is on the Pentazocine page.
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