Drug interactions
Phentermine + Pirbuterol
Severity: Moderate
Phentermine and Pirbuterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phentermine is a sympathomimetic stimulant and adds to the cardiovascular and CNS stimulation of pirbuterol. Heart rate and blood pressure may rise, with palpitations, tremor or insomnia.
What this interaction means in plain words
Phentermine and Pirbuterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive sympathomimetic effects, with phentermine releasing catecholamines and pirbuterol directly stimulating beta receptors.
What to do
Monitor heart rate and blood pressure, and counsel the patient to report palpitations. Reduce the dose or stop one drug if symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Phentermine with Pirbuterol?
MediHelp rates the interaction as moderate. Phentermine and Pirbuterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phentermine is a sympathomimetic stimulant and adds to the cardiovascular and CNS stimulation of pirbuterol. Heart rate and blood pressure may rise, with palpitations, tremor or insomnia.
How serious is the interaction between Phentermine and Pirbuterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure, and counsel the patient to report palpitations. Reduce the dose or stop one drug if symptoms occur.
What other medicines interact with Phentermine?
MediHelp also lists interactions of Phentermine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Phentermine page.
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