Drug interactions
Phentermine + Terbutaline
Severity: Moderate
Phentermine and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phentermine is a sympathomimetic amine that raises blood pressure and heart rate, and terbutaline adds beta-adrenergic stimulation. Together they may cause palpitations, tremor, anxiety, hypertension and arrhythmias.
What this interaction means in plain words
Phentermine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Phentermine belongs to Central Nervous System; Terbutaline belongs to Respiratory.
Why it happens
Additive sympathomimetic stimulation from norepinephrine release and direct beta-2 agonism.
What to do
Monitor blood pressure, heart rate and symptoms of palpitations during co-use. Avoid or reconsider phentermine in patients with significant cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Phentermine and Terbutaline, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Terbutaline
Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Phentermine with Terbutaline?
MediHelp rates the interaction as moderate. Phentermine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phentermine is a sympathomimetic amine that raises blood pressure and heart rate, and terbutaline adds beta-adrenergic stimulation. Together they may cause palpitations, tremor, anxiety, hypertension and arrhythmias.
How serious is the interaction between Phentermine and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and symptoms of palpitations during co-use. Avoid or reconsider phentermine in patients with significant cardiovascular disease.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
