Drug interactions
Phytoestrogens + Piroxicam
Severity: Minor
Phytoestrogens and Piroxicam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phytoestrogens such as isoflavones may have mild antiplatelet activity, and a theoretical additive bleeding tendency with NSAIDs has been proposed. Clinical evidence is weak.
What this interaction means in plain words
Phytoestrogens and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak antiplatelet effects of isoflavones add to NSAID platelet inhibition; not firmly established.
What to do
No routine action is required. Watch for unusual bruising or bleeding in patients also on anticoagulants.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Frequently asked questions
Can I take Phytoestrogens with Piroxicam?
MediHelp rates the interaction as minor. Phytoestrogens and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phytoestrogens such as isoflavones may have mild antiplatelet activity, and a theoretical additive bleeding tendency with NSAIDs has been proposed. Clinical evidence is weak.
How serious is the interaction between Phytoestrogens and Piroxicam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is required. Watch for unusual bruising or bleeding in patients also on anticoagulants.
What other medicines interact with Piroxicam?
MediHelp also lists interactions of Piroxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Piroxicam page.
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