Drug interactions
Pivmecillinam + Valganciclovir
Severity: Minor
Pivmecillinam and Valganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ganciclovir, the active form of valganciclovir, and mecillinam are both renally eliminated, partly by tubular secretion. Competition could modestly raise levels of either drug. Clinically relevant effects are poorly documented.
What this interaction means in plain words
Pivmecillinam and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Pivmecillinam belongs to Anti Bacterial; Valganciclovir belongs to Anti Virals.
Why it happens
Possible competition for renal tubular secretion.
What to do
No routine change is needed; dose according to creatinine clearance and monitor renal function and blood counts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Valganciclovir
Other interactions of Pivmecillinam
- Doxycycline + Pivmecillinam Moderate
- Minocycline + Pivmecillinam Moderate
- Pivmecillinam + Probenecid Moderate
- Pivmecillinam + Tetracycline Moderate
- Acetylsalicylic acid + Pivmecillinam Minor
- Acyclovir + Pivmecillinam Minor
Frequently asked questions
Can I take Pivmecillinam with Valganciclovir?
MediHelp rates the interaction as minor. Pivmecillinam and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ganciclovir, the active form of valganciclovir, and mecillinam are both renally eliminated, partly by tubular secretion. Competition could modestly raise levels of either drug. Clinically relevant effects are poorly documented.
How serious is the interaction between Pivmecillinam and Valganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; dose according to creatinine clearance and monitor renal function and blood counts.
What other medicines interact with Valganciclovir?
MediHelp also lists interactions of Valganciclovir with, for example, Didanosine, Ganciclovir, Liposomal doxorubicin. The full list is on the Valganciclovir page.
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