Drug interactions
Pravastatin + Telmisartan
Severity: Minor
Pravastatin and Telmisartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telmisartan may inhibit OATP1B1 in vitro, which could theoretically increase pravastatin exposure and myopathy risk. Clinically important effects have not been well established.
What this interaction means in plain words
Pravastatin and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Pravastatin belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Possible OATP1B1 inhibition by telmisartan may reduce hepatic uptake of pravastatin; this is largely theoretical.
What to do
No routine dose change is needed; counsel patients to report unexplained muscle symptoms and check creatine kinase if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Pravastatin
Frequently asked questions
Can I take Pravastatin with Telmisartan?
MediHelp rates the interaction as minor. Pravastatin and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Telmisartan may inhibit OATP1B1 in vitro, which could theoretically increase pravastatin exposure and myopathy risk. Clinically important effects have not been well established.
How serious is the interaction between Pravastatin and Telmisartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; counsel patients to report unexplained muscle symptoms and check creatine kinase if they occur.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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