Drug interactions
Prednisone + Tabelecleucel
Severity: Moderate
Prednisone and Tabelecleucel: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids are lymphocytotoxic and may suppress the T cells in tabelecleucel, reducing efficacy. Higher doses have not been evaluated.
What this interaction means in plain words
Prednisone and Tabelecleucel can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Prednisone belongs to Endocrine; Tabelecleucel belongs to Oncology.
Why it happens
Glucocorticoid-mediated suppression of T-cell function and survival.
What to do
Reduce the corticosteroid dose as far as clinically safe, keeping prednisone at or below 1 mg/kg daily.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tabelecleucel
- Brentuximab vedotin + Tabelecleucel Moderate
Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Frequently asked questions
Can I take Prednisone with Tabelecleucel?
MediHelp rates the interaction as moderate. Prednisone and Tabelecleucel can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids are lymphocytotoxic and may suppress the T cells in tabelecleucel, reducing efficacy. Higher doses have not been evaluated.
How serious is the interaction between Prednisone and Tabelecleucel?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reduce the corticosteroid dose as far as clinically safe, keeping prednisone at or below 1 mg/kg daily.
What other medicines interact with Tabelecleucel?
MediHelp also lists interactions of Tabelecleucel with, for example, Brentuximab vedotin. The full list is on the Tabelecleucel page.
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