Drug interactions
Prednisone + Ublituximab
Severity: Moderate
Prednisone and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and prednisone suppresses immune function, so combined use may increase the risk of infection. Corticosteroids are also commonly used as premedication for infusion reactions.
What this interaction means in plain words
Prednisone and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Prednisone belongs to Endocrine; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from B-cell depletion and glucocorticoid effects on immune cells.
What to do
Monitor for signs of infection and use the lowest effective steroid dose and duration. Screen for hepatitis B and other relevant infections before treatment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Ublituximab
Frequently asked questions
Can I take Prednisone with Ublituximab?
MediHelp rates the interaction as moderate. Prednisone and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ublituximab depletes B cells and prednisone suppresses immune function, so combined use may increase the risk of infection. Corticosteroids are also commonly used as premedication for infusion reactions.
How serious is the interaction between Prednisone and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection and use the lowest effective steroid dose and duration. Screen for hepatitis B and other relevant infections before treatment.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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