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Drug interactions

Primaquine + Telavancin

Severity: Moderate

Primaquine and Telavancin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Primaquine has been associated with QT prolongation and telavancin may add to the effect. This may increase arrhythmia risk in predisposed patients.

What this interaction means in plain words

Primaquine and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Primaquine belongs to Anti Parasitic; Telavancin belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Additive pharmacodynamic QTc prolongation.

What to do

Check baseline ECG and electrolytes and monitor the QTc during co-administration. Avoid other QT-prolonging drugs where possible.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Primaquine with Telavancin?

MediHelp rates the interaction as moderate. Primaquine and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Primaquine has been associated with QT prolongation and telavancin may add to the effect. This may increase arrhythmia risk in predisposed patients.

How serious is the interaction between Primaquine and Telavancin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes and monitor the QTc during co-administration. Avoid other QT-prolonging drugs where possible.

What other medicines interact with Telavancin?

MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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