Drug interactions
Progesterone natural + Voriconazole
Severity: Minor
Progesterone natural and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole may raise progesterone levels, particularly with oral dosing. This may increase drowsiness, dizziness and other progestogenic effects.
What this interaction means in plain words
Progesterone natural and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Voriconazole inhibits CYP3A4 metabolism of progesterone.
What to do
Monitor for increased sedation or progestogenic effects. Adjust the progesterone dose if symptoms occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Progesterone natural with Voriconazole?
MediHelp rates the interaction as minor. Progesterone natural and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voriconazole may raise progesterone levels, particularly with oral dosing. This may increase drowsiness, dizziness and other progestogenic effects.
How serious is the interaction between Progesterone natural and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased sedation or progestogenic effects. Adjust the progesterone dose if symptoms occur.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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