Drug interactions
Propranolol + Treprostinil
Severity: Minor
Propranolol and Treprostinil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a vasodilator that lowers blood pressure, and propranolol can add to this effect. Hypotension may be more pronounced at initiation or dose increases.
What this interaction means in plain words
Propranolol and Treprostinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Propranolol belongs to Cardiovascular; Treprostinil belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering effects.
What to do
Monitor blood pressure when starting or titrating treprostinil in patients taking propranolol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
- Arformoterol + Propranolol Major
Other interactions of Treprostinil
Frequently asked questions
Can I take Propranolol with Treprostinil?
MediHelp rates the interaction as minor. Propranolol and Treprostinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Treprostinil is a vasodilator that lowers blood pressure, and propranolol can add to this effect. Hypotension may be more pronounced at initiation or dose increases.
How serious is the interaction between Propranolol and Treprostinil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when starting or titrating treprostinil in patients taking propranolol.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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