Drug interactions
Quizartinib + Thioridazine
Severity: Contraindicated
Quizartinib and Thioridazine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs prolong the QT interval. Combined use increases the risk of torsades de pointes and sudden cardiac death.
What this interaction means in plain words
Quizartinib and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Quizartinib belongs to Oncology; Thioridazine belongs to Central Nervous System.
Why it happens
Additive QTc prolongation.
What to do
Avoid the combination and use a non-QT-prolonging antipsychotic. If concurrent use cannot be avoided, check ECG frequently and correct electrolytes.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Other interactions of Quizartinib
- Quizartinib + Ziprasidone Contraindicated
- Alfuzosin + Quizartinib Major
- Amiodarone + Quizartinib Major
- Amitriptyline + Quizartinib Major
- Amobarbital + Quizartinib Major
- Apalutamide + Quizartinib Major
Frequently asked questions
Can I take Quizartinib with Thioridazine?
MediHelp rates the interaction as contraindicated. Quizartinib and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval. Combined use increases the risk of torsades de pointes and sudden cardiac death.
How serious is the interaction between Quizartinib and Thioridazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-QT-prolonging antipsychotic. If concurrent use cannot be avoided, check ECG frequently and correct electrolytes.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
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