Drug interactions
Albuterol + Ranolazine
Severity: Moderate
Albuterol and Ranolazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ranolazine prolongs the QT interval in a dose-related way, and albuterol can cause hypokalemia, tachycardia and QT prolongation at higher doses. Combined use may increase the risk of arrhythmia, especially with electrolyte disturbances.
What this interaction means in plain words
Albuterol and Ranolazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist induced hypokalemia adding to the risk.
What to do
Monitor potassium and magnesium and obtain an ECG if high-dose or frequent albuterol is needed. Correct electrolyte abnormalities before use.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ranolazine
- Adagrasib + Ranolazine Contraindicated
- Amobarbital + Ranolazine Contraindicated
- Apalutamide + Ranolazine Contraindicated
- Butabarbital + Ranolazine Contraindicated
- Carbamazepine + Ranolazine Contraindicated
- Clarithromycin + Ranolazine Contraindicated
Frequently asked questions
Can I take Albuterol with Ranolazine?
MediHelp rates the interaction as moderate. Albuterol and Ranolazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ranolazine prolongs the QT interval in a dose-related way, and albuterol can cause hypokalemia, tachycardia and QT prolongation at higher doses. Combined use may increase the risk of arrhythmia, especially with electrolyte disturbances.
How serious is the interaction between Albuterol and Ranolazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and magnesium and obtain an ECG if high-dose or frequent albuterol is needed. Correct electrolyte abnormalities before use.
What other medicines interact with Ranolazine?
MediHelp also lists interactions of Ranolazine with, for example, Adagrasib, Amobarbital, Apalutamide. The full list is on the Ranolazine page.
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