Drug interactions
Rilpivirine + Salbutamol
Severity: Minor
Rilpivirine and Salbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rilpivirine at supratherapeutic doses prolongs the QT interval, and salbutamol may add a small risk through hypokalemia and tachycardia. At standard doses the clinical effect is probably small but can matter in patients with other risk factors.
What this interaction means in plain words
Rilpivirine and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Rilpivirine belongs to Anti Virals; Salbutamol belongs to Respiratory.
Why it happens
Possible additive QT prolongation, with beta-2 agonist induced hypokalemia.
What to do
No routine action is needed at standard doses. Check ECG and potassium if the patient has other QT risk factors or needs high-dose salbutamol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Salbutamol
Other interactions of Rilpivirine
- Carbamazepine + Rilpivirine Contraindicated
- Dexamethasone + Rilpivirine Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Efavirenz + Rilpivirine Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Esomeprazole + Rilpivirine Contraindicated
Frequently asked questions
Can I take Rilpivirine with Salbutamol?
MediHelp rates the interaction as minor. Rilpivirine and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rilpivirine at supratherapeutic doses prolongs the QT interval, and salbutamol may add a small risk through hypokalemia and tachycardia. At standard doses the clinical effect is probably small but can matter in patients with other risk factors.
How serious is the interaction between Rilpivirine and Salbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at standard doses. Check ECG and potassium if the patient has other QT risk factors or needs high-dose salbutamol.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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