Drug interactions
Rosiglitazone + Tongkat ali
Severity: Minor
Rosiglitazone and Tongkat ali: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tongkat ali (Eurycoma longifolia) has shown glucose-lowering activity in animal studies. With rosiglitazone it may add to glucose lowering and increase hypoglycemia risk, though human data are scarce.
What this interaction means in plain words
Rosiglitazone and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic effect; mechanism not well established.
What to do
Monitor blood glucose in patients taking tongkat ali. Reduce the antidiabetic dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Insulin aspart + Rosiglitazone Major
- Insulin degludec / insulin aspart + Rosiglitazone Major
- Insulin degludec-insulin aspart + Rosiglitazone Major
- Insulin degludec-liraglutide + Rosiglitazone Major
Frequently asked questions
Can I take Rosiglitazone with Tongkat ali?
MediHelp rates the interaction as minor. Rosiglitazone and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tongkat ali (Eurycoma longifolia) has shown glucose-lowering activity in animal studies. With rosiglitazone it may add to glucose lowering and increase hypoglycemia risk, though human data are scarce.
How serious is the interaction between Rosiglitazone and Tongkat ali?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose in patients taking tongkat ali. Reduce the antidiabetic dose if hypoglycemia occurs.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
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