Drug interactions
Albuterol + Trazodone
Severity: Minor
Albuterol and Trazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tricyclic antidepressants can potentiate the cardiovascular effects of beta-agonists, but trazodone is not a tricyclic and has little noradrenaline reuptake inhibition. Trazodone's alpha-blocking effects may cause some blood pressure changes, but a clinically significant interaction is not well established.
What this interaction means in plain words
Albuterol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Not well established; possible minor additive cardiovascular effects.
What to do
No routine change is needed. Monitor heart rate and blood pressure in patients with cardiac disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Trazodone
- Arsenic trioxide + Trazodone Contraindicated
- Ibutilide + Trazodone Contraindicated
- Isocarboxazid + Trazodone Contraindicated
- Levoketoconazole + Trazodone Contraindicated
- Methylene blue + Trazodone Contraindicated
- Phenelzine + Trazodone Contraindicated
Frequently asked questions
Can I take Albuterol with Trazodone?
MediHelp rates the interaction as minor. Albuterol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tricyclic antidepressants can potentiate the cardiovascular effects of beta-agonists, but trazodone is not a tricyclic and has little noradrenaline reuptake inhibition. Trazodone's alpha-blocking effects may cause some blood pressure changes, but a clinically significant interaction is not well established.
How serious is the interaction between Albuterol and Trazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor heart rate and blood pressure in patients with cardiac disease.
What other medicines interact with Trazodone?
MediHelp also lists interactions of Trazodone with, for example, Arsenic trioxide, Ibutilide, Isocarboxazid. The full list is on the Trazodone page.
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