Drug interactions
Albuterol + Trimipramine
Severity: Moderate
Albuterol and Trimipramine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tricyclic antidepressants may potentiate the cardiovascular effects of beta agonists such as albuterol, causing tachycardia, palpitations or arrhythmia. The risk is mainly with systemic or high-dose use and in patients with heart disease.
What this interaction means in plain words
Albuterol and Trimipramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic cardiovascular stimulation, with tricyclic effects on catecholamine reuptake.
What to do
Monitor heart rate and rhythm, especially with frequent or high-dose albuterol use. Review the need for tricyclic therapy in patients with cardiac disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Trimipramine
- Disopyramide + Trimipramine Contraindicated
- Dofetilide + Trimipramine Contraindicated
- Ibutilide + Trimipramine Contraindicated
- Isocarboxazid + Trimipramine Contraindicated
- Pentamidine + Trimipramine Contraindicated
- Phenelzine + Trimipramine Contraindicated
Frequently asked questions
Can I take Albuterol with Trimipramine?
MediHelp rates the interaction as moderate. Albuterol and Trimipramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tricyclic antidepressants may potentiate the cardiovascular effects of beta agonists such as albuterol, causing tachycardia, palpitations or arrhythmia. The risk is mainly with systemic or high-dose use and in patients with heart disease.
How serious is the interaction between Albuterol and Trimipramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and rhythm, especially with frequent or high-dose albuterol use. Review the need for tricyclic therapy in patients with cardiac disease.
What other medicines interact with Trimipramine?
MediHelp also lists interactions of Trimipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Trimipramine page.
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