Drug interactions
Saxagliptin + Sulfamethoxypyridazine
Severity: Minor
Saxagliptin and Sulfamethoxypyridazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sulfonamide antibiotics can occasionally lower blood glucose, so using one with saxagliptin may add to hypoglycemia risk. The effect is mainly documented with sulfonylureas, and the risk with saxagliptin alone is small.
What this interaction means in plain words
Saxagliptin and Sulfamethoxypyridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive glucose-lowering effect of sulfonamides; mechanism not established for this pair.
What to do
Counsel patients on hypoglycemia symptoms and check glucose if symptoms occur, particularly with concurrent insulin or sulfonylureas.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Frequently asked questions
Can I take Saxagliptin with Sulfamethoxypyridazine?
MediHelp rates the interaction as minor. Saxagliptin and Sulfamethoxypyridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sulfonamide antibiotics can occasionally lower blood glucose, so using one with saxagliptin may add to hypoglycemia risk. The effect is mainly documented with sulfonylureas, and the risk with saxagliptin alone is small.
How serious is the interaction between Saxagliptin and Sulfamethoxypyridazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients on hypoglycemia symptoms and check glucose if symptoms occur, particularly with concurrent insulin or sulfonylureas.
What other medicines interact with Saxagliptin?
MediHelp also lists interactions of Saxagliptin with, for example, Albiglutide, Amlodipine-benazepril, Aripiprazole. The full list is on the Saxagliptin page.
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