Drug interactions
Scopolamine + Umeclidinium-vilanterol
Severity: Moderate
Scopolamine and Umeclidinium-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Umeclidinium is an inhaled antimuscarinic, and scopolamine is a systemic anticholinergic. Together they may add anticholinergic effects such as dry mouth, urinary retention, blurred vision, constipation and confusion.
What this interaction means in plain words
Scopolamine and Umeclidinium-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Scopolamine belongs to Respiratory; Umeclidinium-vilanterol belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Monitor for anticholinergic effects, especially in older patients or those with glaucoma or urinary retention. Consider an alternative antiemetic if effects emerge.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Umeclidinium-vilanterol
Other interactions of Scopolamine
Frequently asked questions
Can I take Scopolamine with Umeclidinium-vilanterol?
MediHelp rates the interaction as moderate. Scopolamine and Umeclidinium-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Umeclidinium is an inhaled antimuscarinic, and scopolamine is a systemic anticholinergic. Together they may add anticholinergic effects such as dry mouth, urinary retention, blurred vision, constipation and confusion.
How serious is the interaction between Scopolamine and Umeclidinium-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects, especially in older patients or those with glaucoma or urinary retention. Consider an alternative antiemetic if effects emerge.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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