Drug interactions
Selenium + Trientine
Severity: Minor
Selenium and Trientine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Trientine is a chelator and can bind minerals in the gut, so co-administration with mineral supplements may reduce trientine absorption. The effect with selenium specifically is theoretical.
What this interaction means in plain words
Selenium and Trientine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Selenium belongs to Gastrointestinal Tract; Trientine belongs to Miscellaneous.
Why it happens
Possible binding of trientine to mineral supplements in the gastrointestinal tract, reducing absorption.
What to do
Give trientine at least 1 hour before or after selenium supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Selenium
- Alendronate + Selenium Moderate
- Eltrombopag + Selenium Moderate
- Ibandronate + Selenium Moderate
- Penicillamine + Selenium Moderate
- Risedronate + Selenium Moderate
- Baloxavir marboxil + Selenium Minor
Other interactions of Trientine
- Calcium + Trientine Moderate
- Carbonyl iron + Trientine Moderate
- Copper + Trientine Moderate
- Ferrous fumarate + Trientine Moderate
- Ferrous gluconate + Trientine Moderate
- Ferrous sulfate + Trientine Moderate
Frequently asked questions
Can I take Selenium with Trientine?
MediHelp rates the interaction as minor. Selenium and Trientine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Trientine is a chelator and can bind minerals in the gut, so co-administration with mineral supplements may reduce trientine absorption. The effect with selenium specifically is theoretical.
How serious is the interaction between Selenium and Trientine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give trientine at least 1 hour before or after selenium supplements.
What other medicines interact with Selenium?
MediHelp also lists interactions of Selenium with, for example, Alendronate, Eltrombopag, Ibandronate. The full list is on the Selenium page.
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