Drug interactions
Sirolimus + Travelers diarrhea and cholera vaccine inactivated
Severity: Minor
Sirolimus and Travelers diarrhea and cholera vaccine inactivated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sirolimus may diminish the immune response to this inactivated oral vaccine, reducing protection. Being non-live, it poses no added infection risk.
What this interaction means in plain words
Sirolimus and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Sirolimus inhibits mTOR-dependent lymphocyte proliferation, reducing the immune response to vaccination.
What to do
The vaccine may be given; reinforce food and water hygiene measures because protection may be incomplete.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Sirolimus and Travelers diarrhea and cholera vaccine inactivated, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Sirolimus
- Adenovirus types 4 and 7 live + Sirolimus Contraindicated
- Bcg vaccine live + Sirolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Sirolimus Contraindicated
- Ketoconazole + Sirolimus Contraindicated
- Levoketoconazole + Sirolimus Contraindicated
- Measles mumps and rubella vaccine live + Sirolimus Contraindicated
Frequently asked questions
Can I take Sirolimus with Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates the interaction as minor. Sirolimus and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sirolimus may diminish the immune response to this inactivated oral vaccine, reducing protection. Being non-live, it poses no added infection risk.
How serious is the interaction between Sirolimus and Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: The vaccine may be given; reinforce food and water hygiene measures because protection may be incomplete.
What other medicines interact with Sirolimus?
MediHelp also lists interactions of Sirolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Sirolimus page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
