Drug interactions
Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol + Voriconazole
Severity: Minor
Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole can cause hypokalemia, and bowel preparations cause fluid and electrolyte shifts. Electrolyte disturbance increases the risk of QT prolongation and arrhythmia with voriconazole.
What this interaction means in plain words
Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive effects on electrolyte balance, with voriconazole-associated hypokalemia and fluid and electrolyte shifts from bowel cleansing.
What to do
Ensure adequate hydration and check potassium and magnesium before and after bowel preparation in patients with QT risk factors or heart disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol with Voriconazole?
MediHelp rates the interaction as minor. Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voriconazole can cause hypokalemia, and bowel preparations cause fluid and electrolyte shifts. Electrolyte disturbance increases the risk of QT prolongation and arrhythmia with voriconazole.
How serious is the interaction between Sodium sulfate / potassium chloride / magnesium sulfate / polyethylene glycol and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate hydration and check potassium and magnesium before and after bowel preparation in patients with QT risk factors or heart disease.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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