Drug interactions
Solifenacin + Vilanterol / fluticasone furoate inhaled
Severity: Minor
Solifenacin and Vilanterol / fluticasone furoate inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vilanterol is a long-acting beta-agonist that can raise heart rate and affect QT, and solifenacin may add a small QT effect. The clinical impact is usually modest but matters in patients with cardiac disease.
What this interaction means in plain words
Solifenacin and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive effects on cardiac repolarization and heart rate.
What to do
No routine adjustment is needed; check ECG and heart rate in patients with existing QT prolongation, arrhythmia or electrolyte disturbance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Solifenacin
Frequently asked questions
Can I take Solifenacin with Vilanterol / fluticasone furoate inhaled?
MediHelp rates the interaction as minor. Solifenacin and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vilanterol is a long-acting beta-agonist that can raise heart rate and affect QT, and solifenacin may add a small QT effect. The clinical impact is usually modest but matters in patients with cardiac disease.
How serious is the interaction between Solifenacin and Vilanterol / fluticasone furoate inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; check ECG and heart rate in patients with existing QT prolongation, arrhythmia or electrolyte disturbance.
What other medicines interact with Solifenacin?
MediHelp also lists interactions of Solifenacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Solifenacin page.
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