Drug interactions
Somatrogon + Warfarin
Severity: Minor
Somatrogon and Warfarin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone products may increase the activity of some cytochrome P450 enzymes. This could modestly lower warfarin exposure and anticoagulant effect. The evidence is limited and clinical relevance uncertain.
What this interaction means in plain words
Somatrogon and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Somatrogon belongs to Endocrine; Warfarin belongs to Cardiovascular.
Why it happens
Growth hormone may induce CYP450 enzyme activity, increasing warfarin metabolism.
What to do
Check INR after starting or changing somatrogon and adjust the warfarin dose if the INR moves from target.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Warfarin
- Defibrotide + Warfarin Contraindicated
- Ketorolac + Warfarin Contraindicated
- Abciximab + Warfarin Major
- Acetylsalicylic acid + Warfarin Major
- Adagrasib + Warfarin Major
- Amiodarone + Warfarin Major
Other interactions of Somatrogon
- Alogliptin-metformin + Somatrogon Moderate
- Alogliptin-pioglitazone + Somatrogon Moderate
- Alogliptin + Somatrogon Moderate
- Canagliflozin-metformin + Somatrogon Moderate
- Chlorpropamide + Somatrogon Moderate
- Cyclosporin + Somatrogon Moderate
Frequently asked questions
Can I take Somatrogon with Warfarin?
MediHelp rates the interaction as minor. Somatrogon and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone products may increase the activity of some cytochrome P450 enzymes. This could modestly lower warfarin exposure and anticoagulant effect. The evidence is limited and clinical relevance uncertain.
How serious is the interaction between Somatrogon and Warfarin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR after starting or changing somatrogon and adjust the warfarin dose if the INR moves from target.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
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