Drug interactions
Streptomycin + Teicoplanin
Severity: Moderate
Streptomycin and Teicoplanin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have potential for kidney and ear toxicity. Concurrent use may increase the risk of renal impairment and hearing or vestibular damage.
What this interaction means in plain words
Streptomycin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Streptomycin belongs to Anti Bacterial; Teicoplanin belongs to Anti Bacterial.
Why it happens
Additive nephrotoxicity and ototoxicity.
What to do
Monitor renal function and drug levels, and assess auditory and vestibular function during treatment. Adjust doses if renal function worsens.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Streptomycin
Other interactions of Teicoplanin
- Amphotericin b + Teicoplanin Major
- Cidofovir + Teicoplanin Major
- Neomycin + Teicoplanin Major
- Teicoplanin + Tobramycin Major
- Acyclovir + Teicoplanin Moderate
- Adefovir + Teicoplanin Moderate
Frequently asked questions
Can I take Streptomycin with Teicoplanin?
MediHelp rates the interaction as moderate. Streptomycin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have potential for kidney and ear toxicity. Concurrent use may increase the risk of renal impairment and hearing or vestibular damage.
How serious is the interaction between Streptomycin and Teicoplanin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and drug levels, and assess auditory and vestibular function during treatment. Adjust doses if renal function worsens.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.
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