Drug interactions
Sulindac + Tafluprost
Severity: Minor
Sulindac and Tafluprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic NSAIDs may alter the intraocular pressure response to prostaglandin analogue eye drops, with reports pointing in both directions. The clinical effect is unpredictable and usually small.
What this interaction means in plain words
Sulindac and Tafluprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Sulindac belongs to Musculoskeletal; Tafluprost belongs to Genitourinary.
Why it happens
Mechanism is not established; NSAIDs may interfere with prostaglandin-mediated aqueous outflow.
What to do
Monitor intraocular pressure if sulindac is started or stopped in a patient treated with tafluprost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Other interactions of Tafluprost
- Bimatoprost + Tafluprost Moderate
- Latanoprost + Tafluprost Moderate
- Tafluprost + Travoprost Moderate
- Acetylsalicylic acid + Tafluprost Minor
- Celecoxib + Tafluprost Minor
- Diclofenac + Tafluprost Minor
Frequently asked questions
Can I take Sulindac with Tafluprost?
MediHelp rates the interaction as minor. Sulindac and Tafluprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic NSAIDs may alter the intraocular pressure response to prostaglandin analogue eye drops, with reports pointing in both directions. The clinical effect is unpredictable and usually small.
How serious is the interaction between Sulindac and Tafluprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor intraocular pressure if sulindac is started or stopped in a patient treated with tafluprost.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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