Drug interactions
Tacrolimus + Travelers diarrhea and cholera vaccine inactivated
Severity: Minor
Tacrolimus and Travelers diarrhea and cholera vaccine inactivated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tacrolimus may reduce the immune response to the inactivated oral cholera and ETEC vaccine. There is no live-organism risk, but protection may be lower than expected.
What this interaction means in plain words
Tacrolimus and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Immunosuppression from calcineurin inhibition may blunt mucosal and systemic antibody responses.
What to do
The vaccine can be given, but advise strict food and water hygiene as the main protection. Complete dosing before travel.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tacrolimus
- Adenovirus types 4 and 7 live + Tacrolimus Contraindicated
- Bcg vaccine live + Tacrolimus Contraindicated
- Cidofovir + Tacrolimus Contraindicated
- Cyclosporin + Tacrolimus Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Tacrolimus Contraindicated
- Measles mumps and rubella vaccine live + Tacrolimus Contraindicated
Frequently asked questions
Can I take Tacrolimus with Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates the interaction as minor. Tacrolimus and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tacrolimus may reduce the immune response to the inactivated oral cholera and ETEC vaccine. There is no live-organism risk, but protection may be lower than expected.
How serious is the interaction between Tacrolimus and Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: The vaccine can be given, but advise strict food and water hygiene as the main protection. Complete dosing before travel.
What other medicines interact with Tacrolimus?
MediHelp also lists interactions of Tacrolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Cidofovir. The full list is on the Tacrolimus page.
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