Drug interactions
Tamsulosin + Terazosin
Severity: Major
Tamsulosin and Terazosin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining two alpha-1 blockers offers no proven added benefit and increases the risk of orthostatic hypotension, dizziness and syncope.
What this interaction means in plain words
Tamsulosin and Terazosin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Tamsulosin belongs to Genitourinary; Terazosin belongs to Genitourinary.
Why it happens
Additive alpha-1 adrenergic receptor blockade causing vasodilation.
What to do
Avoid concurrent use and keep to one alpha-blocker. If changing agents, stop the first and titrate the second, monitoring standing blood pressure.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Tamsulosin and Terazosin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Tamsulosin
- Alfuzosin + Tamsulosin Major
- Avanafil + Tamsulosin Major
- Ceritinib + Tamsulosin Major
- Clarithromycin + Tamsulosin Major
- Cobicistat + Tamsulosin Major
- Doxazosin + Tamsulosin Major
Frequently asked questions
Can I take Tamsulosin with Terazosin?
MediHelp rates the interaction as major. Tamsulosin and Terazosin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining two alpha-1 blockers offers no proven added benefit and increases the risk of orthostatic hypotension, dizziness and syncope.
How serious is the interaction between Tamsulosin and Terazosin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and keep to one alpha-blocker. If changing agents, stop the first and titrate the second, monitoring standing blood pressure.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
