Drug interactions
Teduglutide + Theophylline
Severity: Moderate
Teduglutide and Theophylline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide enhances intestinal fluid and nutrient absorption and may increase absorption of oral drugs. For theophylline, which has a narrow therapeutic index, higher absorption could raise concentrations and cause toxicity.
What this interaction means in plain words
Teduglutide and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Teduglutide belongs to Endocrine; Theophylline belongs to Respiratory.
Why it happens
Teduglutide improves intestinal absorptive capacity, potentially increasing oral theophylline bioavailability.
What to do
Monitor serum theophylline levels after teduglutide is started and adjust the dose as needed. Watch for signs of toxicity such as nausea, tremor and tachycardia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Teduglutide and Theophylline, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Theophylline
- Riociguat + Theophylline Contraindicated
- Adenosine + Theophylline Major
- Apalutamide + Theophylline Major
- Bupropion + Theophylline Major
- Carvedilol + Theophylline Major
- Cimetidine + Theophylline Major
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Teduglutide with Theophylline?
MediHelp rates the interaction as moderate. Teduglutide and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide enhances intestinal fluid and nutrient absorption and may increase absorption of oral drugs. For theophylline, which has a narrow therapeutic index, higher absorption could raise concentrations and cause toxicity.
How serious is the interaction between Teduglutide and Theophylline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum theophylline levels after teduglutide is started and adjust the dose as needed. Watch for signs of toxicity such as nausea, tremor and tachycardia.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
