Drug interactions
Telavancin + Tetrabenazine
Severity: Moderate
Telavancin and Tetrabenazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetrabenazine causes a modest, dose-related QT prolongation. Telavancin may add to the effect, which raises the risk of torsades de pointes in susceptible patients.
What this interaction means in plain words
Telavancin and Tetrabenazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Telavancin belongs to Anti Bacterial; Tetrabenazine belongs to Central Nervous System.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Check ECG and electrolytes at baseline and monitor the QTc during combined use. Use an alternative antibiotic if the QTc lengthens significantly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Tetrabenazine
- Dronedarone + Tetrabenazine Contraindicated
- Isocarboxazid + Tetrabenazine Contraindicated
- Linezolid + Tetrabenazine Contraindicated
- Phenelzine + Tetrabenazine Contraindicated
- Pimozide + Tetrabenazine Contraindicated
- Procarbazine + Tetrabenazine Contraindicated
Frequently asked questions
Can I take Telavancin with Tetrabenazine?
MediHelp rates the interaction as moderate. Telavancin and Tetrabenazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetrabenazine causes a modest, dose-related QT prolongation. Telavancin may add to the effect, which raises the risk of torsades de pointes in susceptible patients.
How serious is the interaction between Telavancin and Tetrabenazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes at baseline and monitor the QTc during combined use. Use an alternative antibiotic if the QTc lengthens significantly.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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