Drug interactions
Telavancin + Voclosporin
Severity: Moderate
Telavancin and Voclosporin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voclosporin can prolong the QT interval at supratherapeutic exposure, and telavancin also affects QTc. Both are also nephrotoxic, so the combination warrants attention to cardiac and renal safety.
What this interaction means in plain words
Telavancin and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Telavancin belongs to Anti Bacterial; Voclosporin belongs to Miscellaneous.
Why it happens
Additive QT prolongation, along with overlapping nephrotoxicity.
What to do
Monitor the ECG, electrolytes and serum creatinine during combined use. Reassess the need for both agents if the QTc or renal function worsens.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Voclosporin
- Clarithromycin + Voclosporin Contraindicated
- Cyclosporin + Voclosporin Contraindicated
- Ensitrelvir + Voclosporin Contraindicated
- Itraconazole + Voclosporin Contraindicated
- Ketoconazole + Voclosporin Contraindicated
- Posaconazole + Voclosporin Contraindicated
Frequently asked questions
Can I take Telavancin with Voclosporin?
MediHelp rates the interaction as moderate. Telavancin and Voclosporin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voclosporin can prolong the QT interval at supratherapeutic exposure, and telavancin also affects QTc. Both are also nephrotoxic, so the combination warrants attention to cardiac and renal safety.
How serious is the interaction between Telavancin and Voclosporin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the ECG, electrolytes and serum creatinine during combined use. Reassess the need for both agents if the QTc or renal function worsens.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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