Drug interactions
Telavancin + Ziprasidone
Severity: Major
Telavancin and Ziprasidone: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ziprasidone is contraindicated with other drugs known to prolong the QT interval because of the risk of torsades de pointes. Telavancin can lengthen the QTc, so combined use may increase the risk of fatal arrhythmia.
What this interaction means in plain words
Telavancin and Ziprasidone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Telavancin belongs to Anti Bacterial; Ziprasidone belongs to Central Nervous System.
Why it happens
Additive prolongation of ventricular repolarization.
What to do
Avoid the combination and use a non-QT-prolonging antibiotic or antipsychotic. If it cannot be avoided, monitor ECG and electrolytes closely.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Frequently asked questions
Can I take Telavancin with Ziprasidone?
MediHelp rates the interaction as major. Telavancin and Ziprasidone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ziprasidone is contraindicated with other drugs known to prolong the QT interval because of the risk of torsades de pointes. Telavancin can lengthen the QTc, so combined use may increase the risk of fatal arrhythmia.
How serious is the interaction between Telavancin and Ziprasidone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-QT-prolonging antibiotic or antipsychotic. If it cannot be avoided, monitor ECG and electrolytes closely.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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